LGD4033 Smar CAS#1165910-22-4 pure powder Material
LGD 4033 is an orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM) that binds to the androgen receptor with a Ki value of 1 nM.1 In animal models, LGD 4033 displays robust selectivity for muscle versus prostate tissues, anabolic activity in the muscle, and anti-resorptive and anabolic activity in bone.1 LGD 4033 has been abused as a performance-enhancing drug and the identification of its in vitro metabolites has been described.2,3 This product is intended for research and forensic applications.
1.Basaria, S., Collins, L., Dillon, E.L., et al.The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young menJ. Gerontol. A Biol. Sci. Med. Sci.68(1)87-95(2013) 2.Geldof, L., Pozo, O.J., Lootens, L., et al.In vitro metabolism study of a black market product containing SARM LGD-4033Drug Test Anal.9(2)168-178(2016) 3.Thevis, M., Lagojda, A., Kuehne, D., et al.Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the internet and identification of in vitro generated phase-I metabolites for human sports drug testingRapid Commun Mass Spectrom.29(11)991-999(2015)
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LGD4033 Smar CAS#1165910-22-4 pure powder Material
LGD 4033 is an orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM) that binds to the androgen receptor with a Ki value of 1 nM.1 In animal models, LGD 4033 displays robust selectivity for muscle versus prostate tissues, anabolic activity in the muscle, and anti-resorptive and anabolic activity in bone.1 LGD 4033 has been abused as a performance-enhancing drug and the identification of its in vitro metabolites has been described.2,3 This product is intended for research and forensic applications.
1.Basaria, S., Collins, L., Dillon, E.L., et al.The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young menJ. Gerontol. A Biol. Sci. Med. Sci.68(1)87-95(2013) 2.Geldof, L., Pozo, O.J., Lootens, L., et al.In vitro metabolism study of a black market product containing SARM LGD-4033Drug Test Anal.9(2)168-178(2016) 3.Thevis, M., Lagojda, A., Kuehne, D., et al.Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the internet and identification of in vitro generated phase-I metabolites for human sports drug testingRapid Commun Mass Spectrom.29(11)991-999(2015)
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