| Prilocaine Chemical Properties |
| Melting point | 37-38° |
| Boiling point | bp0.1 159-162° |
| density | 1.0117 (rough estimate) |
| refractive index | nD20 1.5298 |
| solubility | Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent). |
| form | neat |
| pka | pKa 7.32 or 7.89 (Uncertain) |
| Water Solubility | 6.169g/L(25 ºC) |
| InChIKey | MVFGUOIZUNYYSO-UHFFFAOYSA-N |
| CAS DataBase Reference | 721-50-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanamide, n-(2-methylphenyl)-2-(propylamino)-(721-50-6) |
| Safety Information |
| HS Code | 2924296000 |
| Hazardous Substances Data | 721-50-6(Hazardous Substances Data) |
Usage:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6~7min and the duration time of about 1.5~2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
[Adverse reactions] once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
[Note] patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.
[Usage and dosage] infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5%~1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
Function
1) Tianeptine Improves Depressive Symptoms
2) Tianeptine Lessens Anxiety, Stress, and PTSD and Symptoms From Stress.
3) Tianeptine Benefits Memory and Learning
4) Tianeptine is an Anti-inflammatory
5) Tianeptine decreases pain
6) Tianeptine Helps Treat Irritable bowel Syndrome
7) Tianeptine Reduces Asthma
Our services
1. Supply top quality products with a reasonable price.
2. Arrange the orders and shipping with your requests on time, According to the different countries export policy provide complete customs clearance documents.
3. Samples can be arranged for testing and Unconditional assume responds.
4. Provide a price trend, ensure the clients can know about marketing informations in time.
Packing and Shipping:
| Prilocaine Chemical Properties |
| Melting point | 37-38° |
| Boiling point | bp0.1 159-162° |
| density | 1.0117 (rough estimate) |
| refractive index | nD20 1.5298 |
| solubility | Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent). |
| form | neat |
| pka | pKa 7.32 or 7.89 (Uncertain) |
| Water Solubility | 6.169g/L(25 ºC) |
| InChIKey | MVFGUOIZUNYYSO-UHFFFAOYSA-N |
| CAS DataBase Reference | 721-50-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanamide, n-(2-methylphenyl)-2-(propylamino)-(721-50-6) |
| Safety Information |
| HS Code | 2924296000 |
| Hazardous Substances Data | 721-50-6(Hazardous Substances Data) |
Usage:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6~7min and the duration time of about 1.5~2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
[Adverse reactions] once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
[Note] patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.
[Usage and dosage] infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5%~1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
Function
1) Tianeptine Improves Depressive Symptoms
2) Tianeptine Lessens Anxiety, Stress, and PTSD and Symptoms From Stress.
3) Tianeptine Benefits Memory and Learning
4) Tianeptine is an Anti-inflammatory
5) Tianeptine decreases pain
6) Tianeptine Helps Treat Irritable bowel Syndrome
7) Tianeptine Reduces Asthma
Our services
1. Supply top quality products with a reasonable price.
2. Arrange the orders and shipping with your requests on time, According to the different countries export policy provide complete customs clearance documents.
3. Samples can be arranged for testing and Unconditional assume responds.
4. Provide a price trend, ensure the clients can know about marketing informations in time.
Packing and Shipping:
