Pharm Intermediates Lesinurad RDEA594 CAS No. 878672-00-5

Product Description

  Supply Lesinurad with purity of 99% 878672-00-5 with fast delivery and good package

Product name:

 Lesinurad
Synonyms:  RDEA 594
CAS No.:  878672-00-5
Assay:  99%min
Molecular Formula:  C17H14BrN3O2S
Character:  white crystalline powder



                                          


  Function

1) Lesinurad is used in combination with a xanthine oxidase inhibitor, such as allopurinol, for treating hyperuricemia (high levels of uric acid in the blood serum) associated with gout. It is approved only for patients who have not achieved target uric acid levels with a xanthine oxidase inhibitor alone.


2) Mechanism of action


3) Lesinurad inhibits URAT1, a protein that is responsible for reabsorption of uric acid in the kidneys. This leads to increased uric acid excretion with the urine, and consequently lower blood levels. It also inhibits the protein OAT4, which is associated with hyperuricemia caused by diuretic drugs.



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