High Quality SR17018 Pure Powder Manufacturer CAS#2134602-45-0 with Best Price

Product Description


Specification 

Name SR17018
CAS

2134602-45-0

Purity  98-99%
Grade Standard  Medicine Grade,Food Grade
MF

 

 C19H18Cl3N3O

MW 410.72
Test Method  HPLC
Other Name

 SR17018Powder 

Appearance  White Powder
Brand  MT

Names

Name SR17018

 SR17018 Biological Activity

Description SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
Related Catalog
Target

EC50: 97 nM (MOR)[1]

In Vitro SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. SR17018 shows no obvious effect on inducing βarrestin2 recruitment to the MOR at below 10 μM. SR17018 promotes signaling through G proteins or βarrestin2[1].
References

[1]. Schmid CL, et al. Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 2017 Nov 16;171(5):1165-1175.e13.

 Chemical & Physical Properties

Molecular Formula C19H18Cl3N3O
Molecular Weight 410.72
Storage condition 2-8℃


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