7,8-dihydroxyflavonCAS 38183-03-8 manufactuer
Product Show
| Name | 7,8-dihydroxyflavone |
| CAS | 38183-03-8 |
| Purity | 99% |
| Grade Standard | Medicine Grade |
| Sample | 7,8-dihydroxyflavone |
| COA | 7,8-dihydroxyflavone |
| Test Method | HPLC |
| Other Name | 7,8-dihydroxyflavone |
| Appearance | White Powder |
| Brand | MT |
| Description | 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1]. |
|---|---|
| Related Catalog | |
| Target | TrkB[1] |
| In Vitro | 7,8-Dihydroxyflavone (500 nM) protects the primary cortical neurons and locus coeruleus (LC) neurons from Aβ-induced toxicity and promotes dendritic growth and synaptogenesis[1]. |
| In Vivo | 7,8-Dihydroxyflavone (5 mg/kg/day) prevents synaptic loss and memory deficits in a mouse model of Alzheimer’s Disease[1]. Administration of 7,8- dihydroxyflavone to mice activates TrkB in the brain, inhibits kainic acid-induced toxicity, decreases infarct volumes in stroke in a TrkBdependent manner, and is neuroprotective in an animal model of Parkinson disease[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 494.4±45.0 °C at 760 mmHg |
| Melting Point | 243-246°C |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 |
| Flash Point | 193.5±22.2 °C |
| Exact Mass | 254.057907 |
| PSA | 70.67000 |
| LogP | 2.51 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.699 |
| Storage condition | Store at +4°C |
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2008.
Q2:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account.
Q3:Can you give me a discount price?
Surely,It depend on your qty.
Q4:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q5: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping co st or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q6:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
If you want more info,pls feel free to contact me .
Contact Information
Mrs Rainbow Chen
Mobile:0086 -15958173572(whats app)
Skype/Wechat:rainbow673614
7,8-dihydroxyflavonCAS 38183-03-8 manufactuer
Product Show
| Name | 7,8-dihydroxyflavone |
| CAS | 38183-03-8 |
| Purity | 99% |
| Grade Standard | Medicine Grade |
| Sample | 7,8-dihydroxyflavone |
| COA | 7,8-dihydroxyflavone |
| Test Method | HPLC |
| Other Name | 7,8-dihydroxyflavone |
| Appearance | White Powder |
| Brand | MT |
| Description | 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1]. |
|---|---|
| Related Catalog | |
| Target | TrkB[1] |
| In Vitro | 7,8-Dihydroxyflavone (500 nM) protects the primary cortical neurons and locus coeruleus (LC) neurons from Aβ-induced toxicity and promotes dendritic growth and synaptogenesis[1]. |
| In Vivo | 7,8-Dihydroxyflavone (5 mg/kg/day) prevents synaptic loss and memory deficits in a mouse model of Alzheimer’s Disease[1]. Administration of 7,8- dihydroxyflavone to mice activates TrkB in the brain, inhibits kainic acid-induced toxicity, decreases infarct volumes in stroke in a TrkBdependent manner, and is neuroprotective in an animal model of Parkinson disease[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 494.4±45.0 °C at 760 mmHg |
| Melting Point | 243-246°C |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 |
| Flash Point | 193.5±22.2 °C |
| Exact Mass | 254.057907 |
| PSA | 70.67000 |
| LogP | 2.51 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.699 |
| Storage condition | Store at +4°C |
Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2008.
Q2:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account.
Q3:Can you give me a discount price?
Surely,It depend on your qty.
Q4:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
Q5: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping co st or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q6:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
If you want more info,pls feel free to contact me .
Contact Information
Mrs Rainbow Chen
Mobile:0086 -15958173572(whats app)
Skype/Wechat:rainbow673614
