High Purity Human Growth Hormone CAS 12629-01-5 HGH
Name: Human Growth Hormone
CAS NO.: 12629-01-5
Assay: 99% HPLC
Characteristic: White lyophilized powder
Growth hormone is a kind of peptide hormone, which is secreted by pituitary gland cells.
Growth hormone is composed of 191 amino acid residues with a relative molecular weight
of 22124 daltons. The molecular structure has four α helices, which make growth hormone
combine with its receptor well. The recombinant human growth hormone (rhGH) was secreted
and expressed in E.coli by DNA recombination technology. After separation and purification,
the recombinant human growth hormone (rhGH) solution with high purity was obtained by adding
dressings and freeze-drying. The recombinant human growth hormone for injection was obtained
after passing the test. R-hGH, produced by recombinant DNA technology, has the same effect as
endogenous growth hormone.
Recombinant human growth hormone can promote the growth of all other tissues except nerve
tissue; promote the body's anabolism and protein synthesis; promote fat decomposition; have
antagonistic effect on insulin; inhibit glucose utilization and increase blood glucose. It can promote
the synthesis of various tissues, especially proteins, and promote the division and proliferation of bone,
cartilage, muscle and other tissue cells and protein synthesis, so as to accelerate the growth and development
of bone and muscle. It can be used to treat burn, fracture, trauma, hemorrhagic ulcer, muscular atrophy,
osteoporosis and other diseases. Growth hormone can regulate the metabolism of substances in the body.
Growth hormone mainly through inhibiting muscle and adipose tissue use of glucose, while promoting
gluconeogenesis in the liver and glycogen decomposition, so as to increase blood glucose. Growth hormone
can promote fat decomposition and increase plasma free fatty acids. It can promote protein metabolism,
especially protein synthesis in extrahepatic tissues, promote amino acid entering cells, enhance DNA and RNA synthesis, reduce urine nitrogen, and present a positive balance of nitrogen; enhance lipolysis and antibody formation; inhibit the uptake and utilization of glucose in peripheral tissues, reduce glucose consumption and increase blood glucose level. In August 1996, FDA approved the long-term use of human auxin in adults.
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